Scientific Contribution

Profile - Wee-Eong Teo

Wee-Eong Teo is one of the pioneers in extending the capability of electrospinning to construct unique nanofibrous structures. Notable achivements include developing setups for fabricating nanofibrous tube with controlled fiber alignment, fabrication of continuous nanofiber yarns and three-dimensional nanofiber blocks. He has shown that a dynamic fluid collector is able to modify the resultant electrospun nanofiber structure.

His interest in biomedical devices led to the development of unique nanofibers structures for use as vascular graft, peripheral nerve regeneration graft, bone graft, soft tissue scaffold and nanofiber coating for stents.

Wee Eong believes in the sharing of scientific knowledge and he has published over 20 peered reviewed articles. He has also mentored several students and junior researchers. He is also the co-author of the widely used text book "An Introduction to Electrospinning and Nanofibers" and his reviews are some of the most accessed papers in their respective journals.

Achievements

Pioneered a process to fabricate continuous nanofibrous yarn.
Developed processes to fabricate various 3D nanofibrous structures for use as biological scaffolds
A pioneer in developing hierarchically organized 3D nanofibrous composite for use as bone graft
Development of dynamic fluid flow electrospinning method.
Founder of ElectrospinTech, a web-based portal for various interest groups to find out more about electrospinning and nanofibers.

Scientific Contributions

Publication list (See Citation Index)

Yousefzadeh M., Latifi M., Amani-Tehran M., Teo W. E., and Ramakrishna S. (2012) A Note on the 3D Structural Design of Electrospun Nanofibers, Journal of Engineered Fibers and Fabrics. vol 7 pg. 17-23
Wee-Eong Teo, Ryuji Inai and Seeram Ramakrishna. (2011) Technological advances in electrospinning of nanofibers. Sci. Technol. Adv. Mater. vol 12 pg. 013002. (Downloaded over 500 times within 2 months. Top 3% download in ALL IOP journals in first quarter of 2011. Featured in nanotechweb.org 04 Aug 2011. Featured as one of 15 selected articles published in STAM for its 15th year anniversary) Free download
W.E. Teo, S. Liao, C. Chan and S. Ramakrishna. (2011) Fabrication and characterization of hierarchically organized nanoparticle-reinforced nanofibrous composite scaffolds. Acta. Biomater. vol 7 pg. 193-202.(Featured in Life Science Weekly March 1st, 2011)
Maryam Yousefzadeh, Masoud Latifi, Wee-Eong Teo, Mohammad Amani-Tehran, Seeram Ramakrishna (2011) Producing Continuous Twisted Yarn from Well-Aligned Nanofibers by Water Vortex. Polymer Engineering & Science vol 51 pg. 323-329.4. (Featured in Plastics Research Online, Society of Plastic Engineers, 14 March 2011)
H S Koh, T. Yong, W E Teo, C K Chan, M E Puhaindran, T C Tan, A Lim, B H Lim, S Ramakrishna. (2010) In vivo study on novel nanofibrous intra-luminal guidance channels to promote nerve regeneration. Journal of Neural Engineering vol. 7 pg. 046003 (14pp).
S. Ramakrishna, R. Jose, P.S. Archana, A.S. Nair, R. Balamurugan, J. Venugopal, W.E. Teo (2010) Science and engineering of electrospun nanofibers for advances in clean energy, water filtration, and regenerative medicine. Journal of Materials Science. vol 45 pg. 6283-6312.
W.E. Teo, S. Ramakrishna (2009) Electrospun nanofibers as a platform for multifunctional, hierarchically organized Nanocomposite. Composites Science and Technology vol. 69 pg. 1804-1817. (Top 25 hottest articles in Composites Science and Technology, 1st quarter of 2010)
Wei He, Zuwei Ma, Wee Eong Teo, Yi Xiang Dong, Peter Ashley Robless, Thiam Chye Lim, Seeram Ramakrishna (2009) Tubular nanofiber scaffolds for tissue engineered small-diameter vascular grafts. Journal of Biomedical Materials Research Part A. vol. 90A pg. 205-216.
W.E Teo, S. Liao, C.K. Chan, S. Ramakrishna (2008) Remodeling of Three-dimensional Hierarchically Organized Nanofibrous Assemblies. Current Nanoscience vol. 4 pg. 361-369.
Wee-Eong Teo, Renuga Gopal, Ramakrishnan Ramaseshan Kazutoshi Fujihara, Seeram Ramakrishna (2007) A dynamic liquid support system for continuous electrospun yarn fabrication. Polymer vol. 48 pg. 3400-3405.
Shao Ping Zhong, Wee Eong Teo, Xiao Zhu, Roger Beuerman, Seeram Ramakrishna, Lin Yue Lanry Yung (2007) Development of a novel collagen-GAG nanofibrous scaffold via electrospinning. Materials Science and Engineering C vol. 27 pg. 262-266.
Shaoping Zhong, Wee Eong Teo, Xiao Zhu, Roger W. Beuerman, Seeram Ramakrishna and Lin Yue Lanry Yung (2006) An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture. Journal of Biomedical Materials Research vol. 79A pg. 456-463.
Teo WE, He W, Ramakrishna S (2006) Electrospun scaffold tailored for tissue-specific extracellular matrix. Biotechnology Journal vol. 1 pg. 918-929. (Top download in Biotechnology Journal in September 2006)
W. He, T. Yong, W.E. Teo, Z.W. Ma, R. Inai and S. Ramakrishna (2006) Biodegradable Polymer Nanofiber Mesh to Maintain Functions of Endothelial Cells. Tissue Engineering vol. 12 pg. 2457-2466.
W.E. Teo and S. Ramakrishna (2006) A Review on Electrospinning Design and Nanofibre Assemblies. Nanotechnology vol. 17 pg. 89-106. (Downloaded over 250 times within a month; Top four most assessed articles in category of Materials: synthesis or self-assembly in the year 2006 in Nanotechnology journal)
Seeram Ramakrishna, Kazutoshi Fujihara, Wee-Eong Teo, Thomas Yong, Zuwei Ma, Ramakrishnan Ramaseshan (2006) Electrospun Nanofiber: Solving Global Issues. Materials Today vol. 9 pg. 40 - 50.
Shaoping Zhong, Wee Eong Teo, Xiao Zhu, Roger Beuerman, Seeram Ramakrishna, and Lin Yue Lanry Yung. (2005) Formation of Collagen-Glycosaminoglycan Blended Nanofibrous Scaffolds and Their Biological Properties. Biomacromolecules vol. 6 pg. 2998 - 3004.
He W, Yong T, Teo WE, Ma ZW, Ramakrishna S. (2005) Fabrication and Endothelialization of Collagen-Blended Biodegradable Polymer Nanofibers: potential vascular grafts for the blood vessel tissue engineering. Tissue Engineering vol. 11 pg. 1574-1588.
Wei He, ZuWei Ma, Thomas Yong, Wee Eong Teo and Seeram Ramakrishna. (2005) Fabrication of collagen-coated biodegradable polymer nanofiber mesh and its potential for endothelial cells growth. Biomaterials vol. 26 pg. 7606 - 7615.
W E Teo and S Ramakrishna. (2005) Electrospun fibre bundle made of aligned nanofibres over two fixed points. Nanotechnology vol. 16 pg.1878 - 1884.
W E Teo, M Kotaki, X M Mo and S Ramakrishna. (2005) Porous tubular structures with controlled fibre orientation using a modified electrospinning method. Nanotechnology vol. 16 pg. 918 - 924.

Book and Book Chapters

W E Teo, S Kaur, R Seeram. "Electrospun polymer nanocomposite fibers: fabrication and physical properties", Polymer Nanocomposites: Physical Properties and Applications, edited by S. C. Tjong and Y. W. Mai, Woodhead Publishing Limited. October 2010.
S. Ramakrishna, K. Fujihara, V.K. Ganesh, W.E. Teo and T.C. Lim. "Chapter 7. Science and Engineering of Electrospun Nanofibers", Functional Nanomaterials, edited by K.E. Geckeler and E. Rosenberg, American Scientific Publishers. October 2005.
Seeram Ramakrishna, Kazutoshi Fujihara, Wee-Eong Teo, Teik-Cheng Lim and Zuwei Ma. An Introduction to Electrospinning and Nanofibers. World Scientific Publishing Co. Pte. Ltd. June 2005.

Patents and disclosures

Chan Ching Wan, Wee Eong Teo, Susan Liao, Anitha Panneerselvan. Bioartificial Autologous Graft. US Provisional Patent Application Number: 61/366,170. 21 July 2010.
Koh Huishan, Wee Eong Teo, Kwan-Ho Chan, Seeram Ramakrishna, Ter Chyan Tan, Mark Edward. Biomimetic Fibrous Implant Devices for Nerve Repair. US Provisional Patent Application Number: 61/084,306. 29 July 2008.
Kwan-Ho Chan, Yixiang Dong, Wee Eong Teo, Seeram Ramakrishna. Covered stent coated with aligned or random nanofiber by electrospinning. US Provisional Patent Application Number: 60/984,803. 12 December 2007.
Wee Eong Teo, Kazutoshi Fujihara, Casey Kwan-Ho Chan, Seeram Ramakrishna. Fiber Structures and Process for their preparation. WO 2008/036051, 27 March 2008; Singapore Patent No. 150798, 31 March 2010; US20110180951 A1, 18 Sep 2008
Wee Eong Teo, Kazutoshi Fujihara, Seeram Ramakrishna. Method & Apparatus for producing Fiber Yarn. WO 2007/013858 A1. 01 February 2007.
Teo W.E., M. Kotaki and S. Ramakrishna. An Apparatus and Method for Producing Nanofibres. Singapore Patent No. 117506. 29-July-2004. National University of Singapore.